The Persistent Ostium Primum Atrial Septal Defect

The persistent ostium primum atrial septal defect. (Partial persistent common atrioventricular canal).

The persistent ostium primum atrial septal defect.

Five patients with an ostium primum type of atrial septal defect were studied by clinical and laboratory methods and the diagnosis was verified either at the time of open-heart surgery and/or at autopsy. The atrioventricular valves formed the floor of the defect and were deformed in 4 of the 5 patients. Mitral insufficiency was present as a result of this valvular deformity in these four patien...

Ostium Primum Defect: Factors Causing Deterioration in the Natural History.

The anatomy of the ostium primum atrial septal defect has been known since Rokitansky's description in 1875. However, until the introduction of cardiac catheterization and open heart surgery, information about the physiology and clinical features of this condition lagged behind knowledge of the morbid anatomy. Attempts at surgical correction have influenced the natural history, and information ...

Atrial Septal Defects in the Adult

Nomenclature and Classification There are 3 major types of ASDs or interatrial communications: ostium secundum, ostium primum, and sinus venosus (Figure 1A) defects. The ostium secundum is a true defect of the atrial septum and involves the region of the fossa ovalis. The ostium primum defect is within the spectrum of the atrioventricular (AV) septal defects (Figure 1B; also known as AV canal d...

Genetics of Atrial Septal Defect

Sanchez Cascos, A. (1972). Archives of Disease in Childhood, 47, 581. Genetics of atrial septal defect. Of 109 cases of atrial septal defect, cases with an isolated defect (92 cases) showed a female preponderance (sex ratio 0 64), but there was a higher risk to the sibs of the male patients, suggesting a multifactorial mechanism. Dermatoglyphs showed a large number of whorls on the fingers. In ...